Poster Session One & Burnet Oration Cocktail Function — ASN Events

Poster Session One & Burnet Oration Cocktail Function — ASN Events

Poster Session One & Burnet Oration Cocktail Function

CMTM6 maintains the expression of PD-L1 and regulates anti-tumour immunity - Christina Sparbier

CD83 is a promising biomarker and therapeutic target in Hodgkin Lymphoma (#142)

The role of chemokine receptors in metastatic cancer (#143)

The role of T cells in ovarian cancer (#144)

Farah FA Ahmady

The effect of STING deficiency on development of autoimmune diabetes in NOD mice (#145)

The pathological role of the inflammasome protein asc in parkinson’s disease (#146)

Eduardo A Albornoz

Systemic inflammatory signals suppress local lymph node expansion and B cell immunity (#147)

Yannick O Alexandre

Recognition of non-lipid antigens by Type 2 NKT cells (#148)

Catarina Filipa dos Santos Sa e Almeida

Complete freund’s adjuvant a cheap and effective novel anticancer immunotherapy (#149)

The role of chemokine receptor CXCR3 in the T cell response in the lung following pulmonary immunization with a recombinant Influenza A tuberculosis vaccine (#150)

Mesenchymal stromal cell infusion rapidly attenuates systemic inflammation in patients with chronic obstructive pulmonary disease (#151)

Jesse D Armitage

CXCR6 deficiency alters control of chronic Mycobacterium tuberculosis infection and the inflammatory kinetics of acute respiratory infection (#152)

Anneliese S Ashhurst

Effects of dexamethasone co-medication on chemo-immunotherapy treatment in murine cancer models (#153)

RNA binding protein HuR is required for efficient function and generation of CD4⁺ Foxp3⁺ Treg (#154)

The impact of prior immunity on seasonal influenza vaccine responses in an influenza vaccine-naïve Vietnamese cohort (#155)

Maria Auladell Bernat

Designing a structured, data driven, high complexity human multi-color flow cytometric panel (#156)

Robert Balderas

Investigation of Mast Cell Toll-like receptor 3 in Chronic Fatigue Syndrome/Myalgic Encephalomyelitis and Systemic Mastocytosis patients using the novel application of autoMACS magnetic separation and Flow cytometry (#157)

Cassandra Balinas

Investigation of endocannabinoid-based nanoassemblies targeted to the synovium for the treatment of arthritis (#158)

IS ZEB2 involved in lineage commitment of the human Th1/17 subset, and why does FOXP3 repress it in Treg? (#159)

Lymphocyte-dependent reduction of MHC class II expression on dendritic cells from Human papillomavirus E7 transgenic mice (#160)

Dissecting the relative contributions of resident macrophages and infiltrating monocytes to the control of hepatic Leishmania infection (#161)

Lynette Beattie

Targeting local tumour immunosuppression to enhance chimeric antigen receptor T Cell efficacy in solid cancers (#162)

GILZ: A new regulator of CD8 T cell responses (#163)

Taylah J Bennett

Phenotypic Differences in Peripheral Blood Immune Cells: Contrasting Progressive Multiple Sclerosis with Healthy Controls (#164)

Intracellular bacterial infection promotes the expansion of Tfh1 and B-cell populations (#165)

Nayan Bhattacharyya

A novel mouse model of a human primary immunodeficiency: new insights into the role of PI3K in T cell activation and differentiation (#166)

Regulatory T cell control of T cell reconstitution in a model of bone marrow transplantation (#167)

Caveolin-1 is enriched in CD8+ T cell exosomes, influencing cholesterol homeostasis and intracellular uptake (#168)

Regulation of inflammatory caspase activity during the innate immune response (#169)

Retinoic acid-dependent expression of Hic1 in T cells links Myc-dependent metabolism with the tissue residency gene program (#170)

Michael Bramhall

Characterising self-reactive B cell responses within a polyclonal repertoire (#171)

Jeremy F Brooks

A blood dendritic cell vaccine expands anti-tumour T cell responses in AML (#172)

Christian Bryant

Liposomal delivered antigen-specific tolerising immunotherapy targeting autoreactive CD8+ T cells in NOD mice (#173)

Antibodies cross reacting with self and foreign proteins evolve on consistent trajectories to shed self-binding and then enhance foreign binding (#174)

Deborah Burnett

IFNα subtypes drive distinct anti-cancer activities (#175)

Viral infection of NK cells drives a mature phenotype but inhibits cytolytic function (#176)

Tessa M Campbell

Differential immune responses between animals that clear Group B Streptococcal genital infection and those that remain colonised (#177)

Defining skin-resident T cells in mouse and human (#178)

Clara Castellucci

Elevated serum IgG3 is associated with accelerated progression from clinically isolated syndrome to multiple sclerosis (#179)

Dysregulated IL-21-mediated phosphorylation and nuclear translocation of STAT3 in B-cells of HIV-infected individuals may be associated with increased IFN-α activity (#180)

Characterisation of naïve influenza-specific TCR repertoires in human cord blood (#181)

Jesseka Chadderton

Role of IL-17A in the development of chronic UPEC urinary tract infeciton (#182)

Michelle N Chamoun

Disrupting promoter-enhancer interaction of Bcl11b in T cell by CRISPR/Cas9 (#183)

Silencing of immunogenic antigens during adoptive cell therapy is an acquired resistance mediated by complex epigenetic mechanisms (#184)

Recombinant lipidated survivin is efficiently captured by antigen-presenting cells to trigger antigen cross-presentation and antitumor immunity (#185)

Interplay between Bmp4, Activin βA and Follistatin signalling regulates postnatal thymic epithelial progenitor self-renewal and differentiation (#186)

Phenotypic analysis of T regulatory cells in multiple sclerosis patients (#187)

Christopher H.Y. CHIU

The role of TGFβ in shaping T_RM identity in epithelial and non-epithelial environs (#188)

Susan N Christo

Staphy-PilVax – Can a mucosal vaccine confer protective immunity from Staphylococcus aureus? (#189)

MiR-122 induces neutrophilic inflammation in rhinovirus lung infection and asthma exacerbation by targeting SOCS-1 (#190)

Adam M Collison

Induction of th2 immunity by dendritic cells (#191)

Integrative analysis of miRNA and mRNA response to human malaria infection using systems immunology (#192)

Modulation of murine b cell development during viral encephalitis (#193)

A pilot study characterizing the blood transcriptome of neonates during sepsis using RNA-sequencing (#194)

CD141⁺dendritic cells differentiate from human CD34⁺ hematopoietic stem cells in vitro (#195)

Histone deacetylase 7 is an essential component of macrophage-mediated host defence, promoting phagocytosis, reactive oxygen species production and bacterial clearance (#196)

Kaustav Das Gupta

Identification of generic and pathogen-specific monocyte transcriptomes reveals a largely conserved response in preterm and term newborn infants (#197)

Blood components attenuate dendritic cell responses to TLR ligands in an in vitro model of transfusion (#198)

Modulation of leucocyte populations as a result of coronary artery bypass grafting (#199)

Gain-of-function mutations in Pik3cd result in dysregulation of B cells at multiple stages (#200)

Elissa K Deenick

Key characteristics of antigen presenting cells that dictate unconventional T cell immune responses (#201)

Tamekha Develyn

Expression of the skin-homing receptor E-selectin ligand on Herpes Simplex Virus (HSV)-specific CD4 T cells is independent of Th1 differentiation (#202)

Protection against relapses of disease in a mouse model of multiple sclerosis by a parasite-derived 68-mer peptide (#203)

Aakanksha Dixit

¹⁸F-FDG-PET: A non-invasive tool for imaging colitis (#204)

Nicole Dmochowska

Agonist immunotherapy restores dysfunctional T cells following MEK inhibition and improves therapeutic efficacy (#205)

Sathana Dushyanthen

A novel allergen-encoding immunotherapeutic vaccine modulates cytokine responses of antigen-specific CD4⁺ T cells in peanut allergy (#206)

The role of the nf-kappaB transcription factor RelA in virtual memory CD8 T cells (#207)

CD4 T cell help promotes the effector CD8 T cell response to hepatocyte-expressed antigens (#208)

Influence of CCL17 on the immune defense against Salmonella infection (#209)

A simple, inexpensive cancer immunotherapy: from mouse to Phase I clinical trial (#210)

Therapeutic implication of Programmed cell death-1 ligand 2 (PD-L2) against Melanoma (#211)

Rebecca Faleiro

Can IL-22 therapy make fatty liver, skinny again? (#212)

The chemokine receptor CCR2 is critical for protective memory CD8⁺ T cell generation following viral infection (#213)

Kevin Aaron Fenix

Investigating the role of tumour-associated immune cell subsets in human colorectal cancer liver metastasis (#214)

Kevin Aaron Fenix

Disease-associated gut microbiota and circulating metabolites in systemic lupus erythematosus (#215)

William A Figgett

The role of atypical chemokine receptor ACKR4 in melanoma anti-tumour immunity (#216)

Suppressing autoimmunity in the CNS with human dental pulp stem cells (#217)

Antigen-specific memory T cells are regulated by subcutaneous administration of liposomes encapsulating calcitriol and peptide antigen (#218)

TGF-β signaling suppresses tumor surveillance by converting conventional NK cells into ILC1s (#219)

Donor derived IL-22 is pathogenic following haematopoietic stem cell transplantation (#220)

Investigation of B lymphocyte producing Granzyme B from breast cancer draining lymph nodes (#221)

Abbas A Ghaderi

Investigating the malaria-specific T cell response in the brains of mice infected with Plasmodium berghei ANKA, the causative agent for experimental cerebral malaria (#222)

Nazanin Ghazanfari

Characterisation of Human MR1-restricted T cells (#223)

Nicholas Gherardin

XCR1 expression by dendritic cells promotes NK cell activation during viral infection (#224)

Mature extrathymic CD4⁺CD8⁺ T-cells arise from tissue specific CD4⁺ T-cells (#225)

Jazmina L Gonzalez Cruz

Differential glycosylation of the CD8a homodimer regulates binding to the non-classical MHC-I, H2-Q10 (#226)

Katharine J Goodall

An investigation of CD4+ TCR recognition of an immunodominant HIV epitope in controller individuals (#227)

Progesterone signalling at implantation is required for adequate Treg cell tolerance and fetal growth and viability in late-gestation (#228)

Can autoimmune thyroid disease cause autoimmune attack in the central nervous system (or vice-versa)? (#229)

Antibodies specific for myelin proteolipid protein can inhibit remyelination in vivo (#230)

Macrophage depletion affects placental labyrinth vascularisation independent of fetal alloantigens (#231)

Lymphocyte activation and exhaustion in the natural history of monoclonal gammopathy of undetermined significance (#232)

Ewelina Grywalska

The PD-1/PD-L1 inhibitory pathway is altered in primary glomerulonephritides - preliminary report (#233)

Ewelina Grywalska

Divergent T cell receptor recognition modes of a 13-mer NY-ESO-1 tumour antigenic peptide complexed to HLA-B*07:02 (#234)

Development of human tumour antigen-specific T-cells in a humanised mouse model (#235)

NCOR1 regulates T cell homeostasis and function (#236)

Daniela Hainberger

Killer immunoglobulin-like receptor interactions with human leukocyte antigen ligands are associated with ankylosing spondylitis (#237)

Multiple luminal factors impair epithelial barrier function and activate colonic sensory nerves in Ulcerative Colitis (#238)

Patrick A Hughes

Bacterial sepsis potentiates hypoxic-ischemic brain injury in neonatal mice (#239)