Poster Session Two — ASN Events

Poster Session Two — ASN Events

Poster Session Two

Suppression of medullar erythropoiesis in response to bacterial lipopolysaccharides (LPS) is a TLR4-dependent mechanism with contrasted requirements for G-CSF receptors (#240)

Human CD141+ DC and CD1c+ DC undergo concordant early genetic programming after activation in humanized mice in vivo (#241)

Platelets modulate the leukocyte responses to Toll-like receptor stimulation (#242)

Kathryn E Hally

Hsp90 inhibitors induce caspase-1-independent IL-1β processing and secretion (#243)

Nanoscale bead-based tetramer enrichment and in vitro stimulation results in rapid antigen-specific CD8+ T cell expansion (#244)

Innate immune response in traumatic Spinal Cord Injury (SCI), a beneficial regulatory role for MIS416 (#245)

Masoud Hassanpour Golakani

Examining the development of CD4⁺ T helper, regulatory and memory fates using single-cell genomics (#246)

Development of an in vivo model to study the effects of monoclonal antibody treatment of squamous cell carcinoma (#247)

Xuzhi (Jessica) He

The histone acetylase, HBO1, is necessary for AIRE-regulated transcription in the thymus (#248)

Melanie Heinlein

A phase I / II study of pegylated-Interferon-2alpha for relapsed haematological malignancy after allogeneic haematopoietic progenitor cell transplantation (HPCT) (#249)

Novel CD8⁺ T-cell targets for protection of Indigenous Australians against severe influenza disease (#250)

The protective role of tumour-resident CD8+ T cells in virally-induced human cancers (#251)

Rehana V Hewavisenti

Phosphorylation dynamics and roles in the central nervous system response to interferon-α (#252)

Liver tissue resident memory T cells are formed under various conditions (#253)

A selective Jak1 Inhibitor, Filgotinib (GLPG0634) suppresses lymphocytic infiltration in the salivary gland of non-obese diabetic mice via suppression of BAFF, IP10 and CXCL13 production of salivary gland epithelial cells (#254)

Continentalic acid is responsible for anti-inflammatory and anti-arthritic activities of Aralia continentalis Kitag. ethanol extract in IL-1β-stimulated human osteoarthritis chondrocytes (#255)

Membrane-modified liposomes for vaccine delivery (#256)

Analysis of T cell heterogeneity at the clonal level (#257)

Low density lipoprotein receptor-related protein 1 in inflammatory macrophages (#258)

Depletion of macrophages in elderly, but not young, mice improves IL-2/anti-CD40 immunotherapy and increases anti-tumour cytotoxic T cell activity (#259)

Connie Jackaman

Signatures of acute EBV infection in peripheral B and T cell compartments (#260)

Katherine JL Jackson

Jak inhibitor (tofacitinib) suppresses lymphocytic infiltration in the salivary gland of NOD/Ltj mice the animal model of Sjogren’s syndrome (#261)

Endothelial microvesicles and soluble markers of endothelial injury in critically ill newborns (#262)

Ghrelin-reactive autoantibodies are increased in children with Prader-Willi Syndrome compared to BMI and age-matched controls (#263)

Optimisation of monocyte monolayer assay (mma) for determining the clinical significance of red cell antibodies (#264)

Regulation of HLA-DR and CD38 expression in mild and severe influenza virus infection (#265)

The underlying mechanisms during acute viral bronchiolitis in infants and pre-school children (#266)

Establishing a DNA barcoding approach to track how the immune system and immunotherapies regulate metastatic breast cancer growth at the clonal level (#267)

Parsing the roles of innate and adaptive immune compartments in the lethal, type I IFN-driven, immunopathological disease in LCMV-infected STAT1 KO mice (#268)

Regional variation in specificity and avidity of serum-specific IgE recognition of major group 1 allergens from temperate and subtropical grass pollen in Australia (#269)

Thina H. Kailaivasan

Investigation into the modulation of the red blood cell cytokine profile with non-small cell lung carcinoma and the resulting effect on T-cell activity (#270)

Elisabeth Karsten

Human hypoxic proximal tubule epithelial cells modulate CD1c⁺dendritic cell function (#271)

Andrew Kassianos

Deletion of the epigenetic modifier proteins Suv39h1 and Suv39h2 causes premature immune aging (#272)

Christine R Keenan

Characterizing MAIT cells in human mucosal cancers (#273)

Functional genomics approaches to identifying the role of T-bet mediated inflammation in ankylosing spondylitis (#274)

Vaccine and 4–1BB co-stimulation confers protection against acute myeloid leukemia in mice (#275)

A dendritic cell targeted adenoviral vector facilitates adaptive immune response against human glioma antigen (CMV-IE) and prolongs survival in a human glioma tumor model (#276)

Association between psoriasis and malignancy in the adult general population of United States (#277)

Innate lymphoid cell response to BCG vaccination in mice (#278)

Joanna R Kirman

Lipid excess suppresses NK cell function in B cell lymphoma (#279)

Takumi Kobayashi

Suppression of murine tumor growing through CD8+ CTLs via activated DEC-205+ dendritic cells by sequential administration of α-galactosylceramide in vivo (#280)

Deciphering the epigenetic regulation of humoral responses (#281)

Isabella Y Kong

The impact of Staphylococcal secretomes on cytokine induction and mitochondrial metabolism in skin epithelial cells (#282)

EphA4-Fc antibody treatment exerts protective action in C57BL/6 mice subjected to acute enterobacterial peritonitis (#283)

Changes in peripheral T-cell subsets during Tuberculosis-Diabetes Co-morbidity (#284)

Carine Kunsevi-Kilola

HPV16E7 induced hyperplasia promotes CXCL9/10 expression and induces CXCR3⁺ T cell migration to skin (#285)

The regulation of SMG1 in innate immunity via alternative splicing coupled to nonsense-mediated mRNA decay (#286)

Eliciting innate and adaptive anti-tumour immunity by nanoemulsion co-delivery of tumour antigen and nkt cell ligand to cd8α⁺ dcs (#287)

MIF regulates NLRP3 inflammasome activation and release of IL-1 family cytokines (#288)

An IgG-binding mutant of staphylococcal superantigen-like protein 10 (ssl10) reveals an additional role in complement evasion (#289)

PI3K-δ specific inhibition of regulatory T cells controls metastatic breast cancer via the development of specific anti-tumour T cells (#290)

Increased recruitment of tubulointerstitial human gamma-delta t cells in renal fibrosis and chronic kidney disease (#291)

Characterisation of EBV-specific CD8+ T cells in patients with Diffuse Large B-cell Lymphoma (#292)

Type 1 interferon signalling to dendritic cells limits Murid Herpesvirus-4 spread from the olfactory epithelium (#293)

Immunological mechanisms of chicken susceptibility to H7N9 influenza in the absence of a MBCS (#294)

The development of immune cell subsets expressing Type 2 cytokines in response to parasites and allergens (#295)

Vitamin D supplementation alleviates Th2 immune response by modulating regulatory T cells and memory T cells (#296)

Clodronate liposome-induced macrophage depletion prevents UVR-induced immunosuppression (#297)

Association of a novel long non-coding RNA in 21q22 with Ankylosing Spondylitis susceptibility (#298)

Upregulated 4-1BB (CD137) expression on skin T cells from a mouse model of precancerous skin (#299)

Graham R Leggatt

A toll-like receptor 2 agonist-fused antigen enhanced antitumor immunity by increasing antigen presentation and the CD8 memory T cells population (#300)

Chih-Hsiang Leng

CD4⁺ T cell responses in different age-sex groups of a semelparous marsupial species, the red-tailed phascogale (phascogale calura) (#301)

Corinne Letendre

Estrogen reduces pd-l1 expression in estrogen-receptor positive (er⁺) breast cancer cells in vitro (#302)

Step-wise engagement of the killer T cell function underscored by H3K27me3 demethylation (#303)

Immunological function of alternatively spliced isoforms of MR1 (#304)

Spleen stromal niches which support myeloid restricted hematopoiesis (#305)

Hong Kiat (Don) Lim

Unraveling the dynamics of fate in emergency haematopoiesis using cellular barcoding (#306)

Identification of common host cell transcriptional responses to bacterial infections for drug repurposing (#307)

Dissecting the immunological mechanisms underlying the efficacy of neoadjuvant immunotherapy (#308)

Recombinant lipidated E6E7 of HPV induce strong anti-tumor immunity in animal model (#309)

An optimized live-cell microscopy assay reveals human T-cells primarily respond chemokinetically to chemokines, in contrast to the chemotactic responses of human dendritic cells (#310)

An examination of the persistence and immunogenicity of Plasmodium blood-stage parasites following commencement of chemoprophylaxis with delayed death antimalarial drugs (#311)

High affinity single TCR clone drives a terminally differentiated poly-functional cytotoxic T cell response against viral infection contributing to viral clearance (#312)

Roles for complement C5a receptors, C5aR1 and C5aR2, in regulating melanoma growth (#313)

Different populations of CD11b⁺ dendritic cells drive Th2 responses in the small intestine and colon (#314)

Johannes U Mayer

Identifying human regulatory B cells activated by IL-4-treated mast cells or their microvesicles by mass cytometry (#315)

Felix Marsh-Wakefield

Gene variants of interleukin receptors and their involvement in inherited canine inflammatory diseases: Serendipity or designation? (#316)

Hamutal Mazrier

The regulatory effects of mucosal associated invariant t (MAIT) cells in cancer (#317)

Tobias Meredith

New CARs to enhance cancer immunotherapy in pediatric tumors (#318)

Gene expression profiling reveals the molecular signature of severe carbamazepine-induced hypersensitivity reactions (#319)

Distinctive cellular immunity residues at the at the human fetomaternal interface (#320)

Are you my MAIT? Understanding the role of MAIT cells in colorectal liver metastasis (#321)

Rosemary Millen

Expression of an enterotoxigenic Escherichia coli fusion protein, colonization factor B-heat labile toxin B sub unit (CfaB-LTB), in transgenic plant as edible vaccine candidate (#322)

Seyed Mohammad Moazzeni

IL-22 as a potential therapy to boost mucosal wound healing in the lung (#323)

Md Moniruzzaman

Ablation of commensal microbiota-derived signalling impairs the development of antibody responses to influenza vaccination (#324)

Where and how memory cells are reactivated in the secondary antibody response in the lymph node (#325)

Therapeutic effect of Schwann cell-derived exosome on animal model of multiple sclerosis (#326)

Ghasem Mosayebi

The impact of TLR7 and TLR8 gene variations on antiviral immunity and asthma (#327)

Organoid models to investigate novel treatment options for peritoneal metastases from colorectal cancer (#328)

Vignesh Narasimhan

Tlr4 promote interferon type 1 expression and enhance the th2 response to nippostrongylus brasiliensis independantly of neutrophils extracellular traps secretion (#329)

Christophe Pellefigues

Investigating squamous cell cancer immune evasion in a human cancer progression model (#330)

Katharina Noske

Age-related decline in primary CD8 T cell responses is associated with the development of senescence in virtual memory CD8 T cells (#331)

IL-15 dependent melanoma-resident CD8+ T cell numbers predict patient survival and outcome of anti-PD1 therapy (#332)

Mainthan Palendira

Nlrp3 a double edged sword in colitis and colorectal cancer (#333)

Agampodi Promoda Perera

Impact of dietary nanoparticles on immunity (#334)

Gabriela Pinget

Stability and plasticity of pathogenic ccr2-expressing t_h17 cells (#335)

Skin-resident memory T cells form in the melanoma microenvironment and mediate tumour immune surveillance (#336)

Identification of gene signatures associated with liver fibrosis by RNA-sequencing analysis of biopsies from chronic liver disease patients (#337)